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Gregory Bix

Address800 South Limestone Street
204 Sanders Brown Ctr
Lexington KY 405360230
Phone8592183859
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kahle MP, Bix GJ. Successfully Climbing the "STAIRs": Surmounting Failed Translation of Experimental Ischemic Stroke Treatments. Stroke Res Treat. 2012; 2012:374098. PMID: 23326759.
      View in: PubMed
    2. Clarke DN, Al Ahmad A, Lee B, Parham C, Auckland L, Fertala A, Kahle M, Shaw CS, Roberts J, Bix GJ. Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin a5ß1 and ERK-dependent signaling pathways. PLoS One. 2012; 7(9):e45257. PMID: 23028886.
      View in: PubMed
    3. Roberts J, Kahle MP, Bix GJ. Perlecan and the blood-brain barrier: beneficial proteolysis? Front Pharmacol. 2012; 3:155. PMID: 22936915.
      View in: PubMed
    4. Kahle MP, Lee B, Pourmohamad T, Cunningham A, Su H, Kim H, Chen Y, McCulloch CE, Barbaro NM, Lawton MT, Young WL, Bix GJ. Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue. Neuroreport. 2012 Jul 11; 23(10):627-30. PMID: 22643235.
      View in: PubMed
    5. Dirisala VR, Jeevan A, Bix G, Yoshimura T, McMurray DN. Molecular cloning and expression of the IL-10 gene from guinea pigs. Gene. 2012 Apr 25; 498(1):120-7. PMID: 22349028.
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    6. Saini MG, Bix GJ. Oxygen-glucose deprivation (OGD) and interleukin-1 (IL-1) differentially modulate cathepsin B/L mediated generation of neuroprotective perlecan LG3 by neurons. Brain Res. 2012 Feb 15; 1438:65-74. PMID: 22244880.
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    7. Saini MG, Pinteaux E, Lee B, Bix GJ. Oxygen-glucose deprivation and interleukin-1a trigger the release of perlecan LG3 by cells of neurovascular unit. J Neurochem. 2011 Nov; 119(4):760-71. PMID: 21919908.
      View in: PubMed
    8. Lee B, Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents. J Clin Invest. 2011 Aug; 121(8):3005-23. PMID: 21747167.
      View in: PubMed
    9. Al Ahmad A, Lee B, Stack J, Parham C, Campbell J, Clarke D, Fertala A, Bix GJ. Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro. Brain Res. 2010 Nov 11; 1360:28-39. PMID: 20846515.
      View in: PubMed
    10. Bix G, Iozzo RV. Novel interactions of perlecan: unraveling perlecan's role in angiogenesis. Microsc Res Tech. 2008 May; 71(5):339-48. PMID: 18300285.
      View in: PubMed
    11. Bix G, Iozzo RA, Woodall B, Burrows M, McQuillan A, Campbell S, Fields GB, Iozzo RV. Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor. Blood. 2007 May 1; 109(9):3745-8. PMID: 17197432.
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    12. Bix G, Castello R, Burrows M, Zoeller JJ, Weech M, Iozzo RA, Cardi C, Thakur ML, Barker CA, Camphausen K, Iozzo RV. Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism. J Natl Cancer Inst. 2006 Nov 15; 98(22):1634-46. PMID: 17105986.
      View in: PubMed
    13. Zhu JX, Goldoni S, Bix G, Owens RT, McQuillan DJ, Reed CC, Iozzo RV. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. J Biol Chem. 2005 Sep 16; 280(37):32468-79. PMID: 15994311.
      View in: PubMed
    14. Bix G, Iozzo RV. Matrix revolutions: "tails" of basement-membrane components with angiostatic functions. Trends Cell Biol. 2005 Jan; 15(1):52-60. PMID: 15653078.
      View in: PubMed
    15. Gonzalez EM, Reed CC, Bix G, Fu J, Zhang Y, Gopalakrishnan B, Greenspan DS, Iozzo RV. BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan. J Biol Chem. 2005 Feb 25; 280(8):7080-7. PMID: 15591058.
      View in: PubMed
    16. Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol. 2004 Jul 5; 166(1):97-109. PMID: 15240572.
      View in: PubMed
    17. Clark GD, Zorumski CF, McNeil RS, Happel LT, Ovella T, McGuire S, Bix GJ, Swann JW. Neuronal platelet-activating factor receptor signal transduction involves a pertussis toxin-sensitive G-protein. Neurochem Res. 2000 May; 25(5):603-11. PMID: 10905621.
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    18. Hirotsune S, Fleck MW, Gambello MJ, Bix GJ, Chen A, Clark GD, Ledbetter DH, McBain CJ, Wynshaw-Boris A. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet. 1998 Aug; 19(4):333-9. PMID: 9697693.
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    19. Bix GJ, Clark GD. Platelet-activating factor receptor stimulation disrupts neuronal migration In vitro. J Neurosci. 1998 Jan 1; 18(1):307-18. PMID: 9412509.
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    20. Bix GJ, Clark GD. Elvax as a slow-release delivery agent for a platelet-activating factor receptor agonist and antagonist. J Neurosci Methods. 1997 Nov 7; 77(1):67-74. PMID: 9402559.
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    21. Clark GD, McNeil RS, Bix GJ, Swann JW. Platelet-activating factor produces neuronal growth cone collapse. Neuroreport. 1995 Dec 15; 6(18):2569-75. PMID: 8741765.
      View in: PubMed
    22. Clark GD, McNeil RS, Bix GJ, Swann JW. Lipids as axon guidance molecules? Neuroreport. 1995 Dec 15; 6(18):2446. PMID: 8741737.
      View in: PubMed
    23. Didier M, Bix G, Berman SA, Bursztajn S. Expression of the alpha 4 neuronal nicotinic acetylcholine receptor subunit in the developing mouse hippocampus. Int J Dev Neurosci. 1995 Nov; 13(7):703-13. PMID: 8787861.
      View in: PubMed
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